Renin

A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.

Also Known As:

Big Renin; Cryorenin; Inactive Renin; Pre-Prorenin; Preprorenin; Prorenin; Angiotensin Forming Enzyme; Pre Prorenin; Renin, Big; Renin, Inactive; Angiotensin-Forming Enzyme; Angiotensinogenase

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Endopeptidases: 633
        Aspartic Acid Endopeptidases: 2
        Renin: 12564
      - Proprotein Convertases: 494
        Renin: 12564
      - Aspartic Acid Proteases: 410
        Aspartic Acid Endopeptidases: 2
        Renin: 12564

D G Butler Selected Research

D G Butler Research Topics

Disease

Drug/Important Bio-Agent (IBA)